Laboratory
Science Research

Welcome to TREND

The University of Dayton’s Center for Tissue Regeneration & Engineering at Dayton (TREND) aims to understand the basic biology of how damaged tissues and organs can regenerate. Given the ability of cells in the body to participate in repair, it is imperative to understand how to harness such a property at will. In this respect, translating these basic concepts to engineer tissues might solve problems associated with poor regeneration and artificial tissues.

The Center is committed to interactions with prominent scientists in the field, by inviting them to the University of Dayton campus for active discussions of new ideas. The Center’s focus areas include research collaboration, advanced academic & research training, and technology transfer.
Scientific Experimentation

Our Mission

The TREND Center promotes and supports research collaborations between university faculty and research scientists and engineers in the area of tissue regeneration and bioengineering. The interests of the Center are in eye, bone and ear regeneration and engineering. However, the Center welcomes new academic and research training in this field leading to MS and Ph.D. degrees and provides opportunities for undergraduate research with the Center faculty. The TREND Center promotes technology transfer by facilitating the availability of the applications, techniques and tools developed by the Center to be commercialized by the biotechnology, pharmaceutical and health care industries.
Test Tubes

The TREND Center makes news

We make headlines with the research we do. The University of Dayton is No. 1 among Catholic universities in sponsored scientific research, and our research volume has more than doubled in the last decade.

Read about our latest achievements >>

Faculty & Staff

Panagiotis Tsonis, Ph.D.
Professor, Department of Biology; Director, TREND Center
937-229-2579
Meet Dr. Tsonis

John Rowe, Ph.D.
Professor, Department of Biology; Chair of TREND Steering Committee
937-229-2508
Meet Dr. Rowe

Donald Comfort, Ph.D.
Assistant Professor, SOE Department of Chemical and Materials Engineering
937-229-2627
Meet Dr. Comfort

Douglas Hansen, Ph.D.
Senior Research Scientist and Group Leader, UDRI Materials Degradation and Electrochemical Engineering
937-229-2517
Meet Dr. Hansen

Karolyn Hansen, Ph.D.
Assistant Professor, Department of Biology
937-229-2141
Meet Dr. Hansen

Madhuri Kango-Singh, Ph.D.
Assistant Professor, Department of Biology
937-229-2531
Meet Dr. Kango-Singh

Carissa Krane, Ph.D.
Associate Professor, Department of Biology
937-229-3427
Meet Dr. Krane

Khalid Lafdi, Ph.D.

Professor, SOE Department of Chemical and Materials Engineering;
Wright Brother Institute Endowed Chair in Nano Materials;
Carbon Group Leader, University of Dayton Research Institute
937-229-2679
Meet Dr. Lafdi

Margaret Pinnell, Ph.D.
Associate Professor, SOE Department of Mechanical and Aerospace Engineering
937-229-2835
Meet Dr. Pinnell

Jayne Robinson, Ph.D.
Professor and Chair, Department of Biology
937-229-2521
Meet Dr. Robinson

Amit Singh, Ph.D.
Assistant Professor, Department of Biology
937-229-2894
Meet Dr. Singh

Robert Wilkens, Ph.D.
Professor and Director, SOE Department of Chemical and Materials Engineering
937-229-2627
Meet Dr. Wilkens

Thomas Williams, Ph.D.
Assistant Professor, Department of Biology
937-229-2198
Meet Dr. Williams

Mary Connolly, Ph.D.
Coordinator of Bio-Research Initiatives, University of Dayton Office for Research
937-229-3493
Meet Dr. Connolly

Students in Lab

Academics

The TREND Center has been quite active in its commitment to academic and research training of students at all levels. The Center has been particularly successful in attracting and retaining top quality graduate and undergraduate students to work on faculty-mentored research projects. TREND's interdisciplinary research programs serve as an excellent model for cross-campus collaboration, involving students and faculty from multiple departments (Biology, Mechanical Engineering, Materials Engineering, Chemical Engineering, and Mathematics).

COURSES OF INTEREST

CME 499/585 & BIO 596: Transport Phenomena in Biological Systems
A team taught, interdisciplinary course in Biological Systems Engineering geared for upper level undergraduate and graduate students offered by Dr. Robert Wilkens (CME) and Dr. Carissa Krane (BIO). The course covered the three core areas of Transport Phenomena (Momentum, Heat, and Mass) as applied to two key biological systems: the respiratory system and cardiovascular systeThe learning outcomes supported cross-training of scientists in the language and mechanistic approaches employed by engineers, whereas engineering students were exposed to the terminology and scientific methods associated with physiological and biomedical processes. The design and implementation of the course is likely to serve as a model for the development of an interdisciplinary team-based curriculum in bioengineering. Enrollment for the first offering was eight students. Educational grant support for the development of this course was partially funded through the LTC Innovations Grant Program. (3 sem. hrs.)

BIO 596: Genome Evolution
A graduate-level course that looks at whether a combined consideration of population genetics and development makes the path of genome evolution predictable. Taught by Thomas Williams, BIO. (3 sem. hrs.)

HST 499: Women’s History/Women’s Health
This CAP Crossing Boundaries course was developed and is co-taught by Dr. Caroline Merithew (HST) and Dr. Carissa Krane (BIO). The course examines an historical framework for exploring the evolution of the biology and medicine of women's health issues as they have changed over time. (3 sem. hrs.)

BIO 412: Genetics of Human Disease
This is biology elective course takes a systems approach to studying various inherited diseases, and discuss current techniques of diagnosis and treatment. Taught by Madhuri Kango-Singh, BIO. (3 sem. hrs.)

Publications

The research of TREND faculty generates a large body of scholarly publications which can be accessed from the link below.

List of recent publications >>

Contact Us

Panagiotis Tsonis, Ph.D.
Professor, Department of Biology; Director, TREND Center
937-229-2579
Meet Dr. Tsonis

John Rowe, Ph.D.
Professor, Department of Biology; Chair of TREND Steering Committee
937-229-2508
Meet Dr. Rowe

Mary Connolly, Ph.D.
Coordinator of Bio-Research Initiatives, University of Dayton Office for Research
937-229-3493
Meet Dr. Connolly