Selected faculty publications.

The research of our interdisciplinary faculty is supported by a rich body of published work. Recent peer-reviewed publications are listed below, by year:


Hoffmann A , PA Tsonis. (2013) "Pattern formation in regenerating tissues". In: Pattern formation in morphogenesis. Springer Proceedings in Mathematics, Vol. 15: Capasso, V.; Gromov, M.; Harel-Bellan, A.; Morozova, N.; Pritchard, L. (Eds.) 15, DOI 10.1007/978-3-642-20164-6_2, Springer-Verlag Berlin Heidelberg 2013.

Vergara MN, PA Tsonis. (2013) "The past, present and future of tissue regeneration". In: Regenerative Pharmacology, G. Christ and K-E. Andersson (eds), Cambridge University Press (in press).


Baddour JA, K Sousounis, PA Tsonis. (2012) "Organ repair and regeneration: An overview. Birth Defects Research" C: Embryo Today 96(1):1-29. doi: 10.1002/bdrc.21006 (2012). Selected for the journal cover.

Call GB, OR Puli, AM Jame, CR Pope, M Kango-Singh, A Singh.* (2012). "Annual Drosophila Research Conference, 2012" Developmental Dynamics. 241:1227-1236. PMID: 22592979 [*Corresponding Author]

Chen CL, MC Schroeder, M Kango-Singh, C Tao, G Halder. (2012) "Tumor suppression by cell competition through regulation of the Hippo pathway". Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):484-9. Epub 2011 Dec 21. PMID: 22190496

Ciobanu C, S Iconaru, E Gyorgy, M Radu, M Costache, A Dinischiotu, P Le Coustumer,, K Lafdi, D Predoi. (2012) "Biomedical properties and preparation of iron oxide-dextran nanostructures by MAPLE technique”. Chemistry Central Journal 2012, 6:17 doi: 10.1186/1752-153X-6-17.

Czarnecki JS, K Lafdi, RM Joseph, PA Tsonis. (2012) "Hybrid carbon-based scaffolds for applications in soft tissue reconstruction". Tissue Engineering Part a, 18(9-10), 946-956 doi: 10.1089/ten.TEA.2011.0533.

Haney C, JJ Rowe, JB Robinson. (2012) "SPIONs increase biofilm formation by Pseudomonas aeruginosa". J of Biomaterials and Bionanotechnology, 3 (4A): 508-518 DOI: 10.4236/jbnb.2012.324052

Hoffmann A, Y Huang, R Suetsugu-Maki, CS Ringelberg, CR Tomlinson, K Del Rio-Tsonis, PA Tsonis. (2012) "Implication of the miR-184 and miR-204 Competitive RNA Network in Control of Secondary Cataracts in Mice". Molecular Medicine 18(1):528-38. doi: 10.2119/molmed.2011.00463

Joseph RM, M Greenberg, K Schroder. (2012) "A Retrospective Analysis of Lesser Metatarsalphalangeal Joint Fusion as a Treatment Option for Hammertoe Pathology Associated with Lesser Metatarsalphalangeal. Instability". J Foot Ankle Surg. 2012 Jan; 51(1): 57-62. doi: 10.1053/j.jfas.2011.10.020.

Joseph RM. (2012) "The Role of The DPM PhD in Advancing Foot and Ankle Surgery". J. Foot Ankle Surg. 2012 May; 51(3): 402- 404. doi: 10.1053/j.jfas.2012.02.003.

Pitychoutis PM, C Dalla, AC Sideris, PA Tsonis, Z Papadopoulou-Daifoti (2012) "5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed". Neuroscience 210:152-67. doi: 10.1016/j.neuroscience.2012.03.003.

Singh A,* KD Irvine. (2012). "Drosophila as a model for understanding development and disease". Developmental Dynamics. 241(1):1-2. (Editorial). PMID: 22174082; *Amit Singh is the guest editor for this special issue.

Singh SR, MK Mishra, M Kango-Singh, SX Hou. (2012) "Generation and staining of intestinal stem cell lineage in adult midgut". Methods Mol Biol. 2012;879:47-69. doi: 10.1007/978-1-61779-815-3_4.

Singh, A. (2012). "Neurodegeneration a means to an end". Journal of Cell Science and Therapy (Editorial). J. Cell Sci. Therapy 3:e107. Doi:10.4172/2157-7013.1000e107.

Sousounis K, CE Haley, J Cao, B Sunchu, PA Tsonis. (2012) "Conservation of the three-dimensional structure in non-homologous or unrelated proteins". Human Genomics Aug 2;6:10. doi: 10.1186/1479-7364-6-10.

Sousounis K and PA Tsonis. (2012) "Patterns of gene expression in microarrays and ESTs from normal and cataractous lenses". Human Genomics 6:14. doi: 10.1186/1479-7364-6-14.

Verghese S, S Bedi, M Kango-Singh*. (2012) Hippo signalling controls Dronc activity to regulate organ size in Drosophila. Cell Death Differ. doi: 10.1038/cdd.2012.48. [* Corresponding Author]


Puli-Roy O, and A Singh. (2011) "Protein trap lines of Drosophila to demonstrate spatio-temporal localization of proteins in an undergraduate lab". Dros. Inf. Serv. 94: 190-196.

Rogers WA and TM Williams. (2011) "Quantitative comparison of cis-Regulatory Element (CRE) activities in transgenic Drosophila melanogaster". Journal of Visualized Experiments. Dec; 58 ( e3395): 1-6. doi: 10.3791/3395.

Bhavsar RB, Nakamura K, Tsonis PA. 2011. "A system for culturing iris pigment epithelial cells to study lens regeneration in newt". doi: 10.3791/2713. J. Vis. Exp. 52.

Call GB, Verghese S, Puli OR, Hemmerle DM, Kango-Singh M, Singh A. 2011. "Annual Drosophila research conference, 2011". Developmental Dynamics. 2011 Aug; 240(8):2042-50. doi: 10.1002/dvdy.22689. PMID: 21761487 (*Co-Corresponding Authors)

Casco-Robles MM, Yamada S, Miura T, Nakamura K, Haynes T, Maki N, Del Rio-Tsonis K, Tsonis PA, Chiba C. 2011. "Expressing exogenous genes in newts by transgenesis". Nature Protocols 6: 600-608. doi:10.1038/nprot.2011.334 *Selected for the journal cover.

Ciobanu CS, Andronescu BE, Stoicu A, Florea, O, Le Coustumer, P, Galaup S, Djouadi A, MevellecJY, Musa I, Massuyeau F, Prodan AM, Lafdi K, Trusca J, Pasuk I, Predoi D. 2011. "Influence Of Annealing Treatment Of Nano-Hydroxyapatite Bioceramics On The Vibrational Properties" Digest Journal Of Nanomaterials And Biostructures. Vol. 6, No 2, April - June 2011, 609 – 624.

Diestelkamp W, Krane CM, and Pinnell M. 2011. "Design of a factorial experiment with randomization restrictions to assess medical device performance on vascular tissue". BMC Medical Research Methodology, 11:75. doi:10.1186/1471-2288-11-75

Eguchi G, Eguchi Y, Nakamura K, Yadav MC, Millán JL, Tsonis PA. 2011. "Regenerative capacity in newts is not altered by repeated regeneration and aging". Nature Communications, 2: 384. July 2011. doi: 10.1038/ncomms1389.

Goldstein DL,Frisbie J, Diller A, Pandey RN, Krane CM. 2010. "Glycerol uptake by erythrocytes from warm- and cold-acclimated Cope's gray treefrogs". J. Comp. Physiol. B. 180(8):1257-1265. DOI: 10.1007/s00360-010-0496-4

Hoffmann A, Tsonis PA. 2011. "raveling backward: De-differentiation to stemness". Molecular Interventions 11: 15-17.

Krane CM,Pinnell M, Gardner C, Thompson M, Coleman J, Wilkens R. 2011. "Mechanical test methods for assessing porcine carotid and uterine artery burst pressure following ex-vivo ultrasonic ligature seal and transection". Journal of Testing and Evaluation. E-published, 4 Jan. 2011.

Meyer K, Rajanahalli P, Ahamed M, Rowe J. Hong Y. 2011. "ZnO nanoparticles induce apoptosis in human dermal fibroblast cells via P53 and p38 pathway". Toxicology in Vitro. doi: 10.1016/j.tiv.2011.08.011).

Mutyam V, Puccetti MV, Frisbie J, Goldstein DL, Krane CM. 2011. "Endo-Porter mediated delivery of morpholinos in erythrocyte suspension cultures from Cope's gray tree frog, Hyla chrysoscelis". BioTechniques, 50(5):329-332.

Mutyam V, Puccetti MV, Frisbie J, Goldstein DL, Krane CM. 2011. "Dynamic regulation of aquaglyceroporin expression in erythrocyte cultures from cold- and warm-acclimated Cope's gray treefrog, Hyla chrysoscelis". J. Expt. Zoology: Part A, 315:424–437.

Posgai R, Cipolla-McCulloch CB, Murphy KR, Hussain SM, Rowe JJ, Nielsen MG. 2011. "Differential toxicity of silver and titanium dioxide nanoparticles on Drosophila melanogaster development, reproductive effort, and viability: Size, coatings and antioxidants matter". Chemosphere 85(1): 34-42. DOI: 10.1016/j.chemosphere.2011.06.040

Rajanahalli P, Meyer K, Zhu L, Wagner BD, Robinson ML, King DA, Hong Y. 2011. "Conversion of Mouse Fibroblasts to Sphere Cells with Differentiation Potential Induced by AlbuMAXI-containing Medium". Frontiers of BioScience, doi.10.2741/502

Rebeiz M and Williams TM. 2011. "Experimental Approaches to Evaluate the Contributions of Candidate Cis- regulatory Mutations to Phenotypic Evolution". In: Orgogozo V, Rockman M, editors. Molecular Methods for Evolutionary Genetics. Humana Press. DOI: 10.1007/978-1-61779-228-1_21

Rogers WA and Williams TM. 2011. "Quantitative comparison of cis-Regulatory Element (CRE) activities in transgenic Drosophila melanogaster". Journal of Visualized Experiments (In press). www.doi:10.3791/3395

Singh A, Tare M, Kango-Singh M, Son W-S, Cho K-O, Choi K-W. 2011. "Opposing interactions between homothorax and Lobe defines the ventral eye margin of Drosophila eye". Dev Biol. doi:10.1016/j.ydbio.2011.08.017.

Singh A, Tare M, Roy Puli O, Oros SM, Modi RM, Nainaparampil JN, Kango-Singh M. 2011. "A glimpse into Dorso-ventral patterning of the Drosophila eye". Dev Dyn (in press). (MKS-Co-Corresponding Author). doi: 10.1002/dvdy.22764

Suetsugu-Maki R, Maki N, Fox TP, Nakamura K, Cowepr-Solari R, Tomlinson CR, Qu H, Lambris JD, Tsonis PA. 2011. "A complement receptor C5a antagonist regulates epithelial to mesenchymal transition and crystallin expression after lens cataract surgery in mice". Mol. Vis. 17: 949-964.

Tare M, Modi RM, Nainaparampil JN, Roy Puli O, Bedi S, Fernandez-Funez P, Kango-Singh M*, Singh A*. 2011. "Activation of JNK signaling mediates amyloid-beta-dependent cell death". PLOS One (in press). (*Co-Corresponding Authors). doi: 10.1371/journal.pone.0024361

Tsonis PA, Haynes T, Maki N, Nakamura K, Casco-Robles MM, Yamada S, Miura T, Chiba C, Del Rio-Tsonis K. 2011. "Controlling gene loss of function in newts with emphasis on lens regeneration". Nature Protocols 6: 593-599. doi:10.1038/nprot.2011.341

Usman M and Singh A. 2011. "A new undergraduate curriculum in Mathematical Biology at the University of Dayton". Journal of STEM Education (12), 5&6: 9-17.

Yoon Y, Mount AS, Hansen KM, Hansen DC. 2011. "Electrochemical characterization of a bioceramic material: The shell of the Eastern oyster Crassostrea virginica". Bioelectrochemistry 81(2):91-98.


Joseph RM, Robinson JD, Sparks L. 2010. "Diabetic Foot Health Education and Amputation Prevention". Health Comm, 2010 25:607-608.

Joseph RM. 2010. "Health Care Reform, Statistical Significance, Effect Size, and the Future of the Profession". J. Foot Ankle Surg. 2010 Jul-Aug;49(4):319-20. DOI: 10.1053/j.jfas.2010.05.001. ISSN: 1067-2516

Maki N, Tsonis PA, Agata K. 2010. "Changes in global histone modifications during dedifferentiation in newt lens regeneration". Mol. Vis. 16: 1893-1897.

Oros SM, Tare M, Kango-Singh M, Singh A. 2010. "Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye". Dev Biol. 2010 Oct 15;346(2):258-71. PMID: 20691679. DOI: 10.1016/j.ydbio.2010.07.030

Tsonis PA. "Lens regeneration". 2010. In: Encyclopedia of Eye and Vision (Elsevier).

Zhang MW, Park H, Guo X, Nakamura K, Raphael RM, Kasper FK, Mikos AG, Tsonis PA. 2010. "Adapting biodegradable oligo(poly9ethylene glycol) fumarate) hydrogels for pigmented epithelial cell encapsulation and lens regeneration". Tissue Engineering 16: 261-267.

Maki N, Martinson J, Nishimura O, Tarui H, Meller J, Tsonis PA, Agata K. 2010. "Expression profiles during dedifferentiation in newt lens regeneration revealed by expressed sequence tags". Mol Vis. 16: 72-78. PMCID: PMC2807617

Singh A, Tsonis PA. 2010. "Focus on Molecules: Six3 - Master or Apprentice?" Experimental Eye Research 90 (2010):535-536. PMID: 20117106 (PDF)

Bhavsar RB, Makley LN, Tsonis PA. 2010. "The other lives of ribosomal proteins". Human Genomics. ISSN: 1473-9542 (Paper) 1479-7364 (Online)

Maki N, Suetsugu-Maki R, Sano S, Nakamura K, Nishimura O, Tarui H, Del Rio-Tsonis K, Ohsumi K, Agata K, Tsonis PA. 2010. "Oocyte-type linker histone B4 is required for transdifferentiation of somatic cells in vivo". FASEB J. doi:10.1096/fj.10-159285

Joseph RM, Robinson JD, Sparks L. 2010. "Foot Health Education and Amputation Prevention". Journal of Health Communication.

Ahamed M, Posgai R, Gorey TJ, Nielsen MG, Hussain SM, Rowe JJ. 2010. "Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster". Toxicology and Applied Pharmacology. 242(3):263-269. PMID: 19874832. DOI: 10.1016/j.taap.2009.10.016

Landsman A, Agnew P, Parish L, Joseph R, Galiano RD. 2010. "Diabetic Foot Ulcers Treated with Becaplermin and TheraGauze, a Moisture-Controlling Smart Dressing: A Randomized, Multicenter, Prospective Analysis". Journal of the American Podiatric Medical Association • Vol 100 • No 3 • May/June 2010.