Anne Crecelius, Ph.D.

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Anne R. Crecelius, Ph.D.

Assistant Professor

  • Full-Time Faculty

Degrees

  • Ph.D. in Cardiovascular Physiology, Colorado State University 
  • M.S. in Cardiovascular Physiology, Colorado State University
  • B.S.E. in Exercise Science, University of Dayton

Courses Taught

  • HSS 114 Introduction to the Health Professions
  • HSS 307 Human Physiology
  • HSS 307L Human Physiology Lab
  • HSS 428 Research in Health and Sport Science 

Professional Activities

  • American Physiological Society, Member
  • The Physiological Society, Member
  • American College of Sports Medicine, Member 

Research Interests

In the Integrative Human Physiology Laboratory, we are interested in integrative cardiovascular control in humans focused on:

  • the interaction between sympathetic neural vasoconstrictor and local metabolic factors in the regulation of muscle blood flow and vascular tone at rest and during stress (e.g. hypoxia, exercise),
  • specific vasodilating pathways (e.g. nitric oxide, prostaglandins, and vascular hyperpolarization) involved in the regulation of vascular tone.
  • potential interventions aimed at improving vascular functioning

Additional interest in:

  • exercise rehabilitation program effects in clinical populations (e.g. post-cardiac event, cancer survivors)
  • scaling and interpretation of physiological performance measures

Please feel free to contact hplab@udayton.edu if you are interested in volunteering in the laboratory or participating in ongoing studies. 

Selected Publications

View on eCommons

Peer-reviewed

Richards, J.C., A.R. Crecelius, D.G. Larson and F.A. Dinenno. Impaired peripheral hypoxic vasodilation in healthy older adults: role of the sympathoadrenal system. Am J Physiol Heart Circ Physiol. In Press. 2017.

Smith, T.M., Broomhall, C.N., and A.R. Crecelius.  Physical and psychological impacts of exercise on cancer rehabilitation patients. Clin J Oncol Nursing. 20(6), 653-659.  2016.

Wald, C.M. and A.R. Crecelius. Health-related quality of life increases similarly in type 2 diabetic versus non-diabetic patients following 7-12 week cardiac rehabilitation. J Cardiopulm Rehab and Preven.36(5):339-45. 2016.

M. Wilson, K. Virgin, K. Haynes, A.R. Crecelius. Effect of Sleep on the Attentiveness of Elementary School Students. Undergraduate Research Journal for the Human Sciences. 15. 2016.  

Crecelius A.R. and F.A. Dinenno.  Vascular regulation via KIR channels and Na+/K+-ATPase. Channels. 9(4):171-2. 2015.

Richards, J.C., A.R.Crecelius, D.G. Larson and F.A. Dinenno. Acute ascorbic acid ingestion increases skeletal muscle blood flow and oxygen consumption via local vasodilation during graded handgrip exercise in older adults. Am J Physiol Heart Circ Physiol. 309(2):H360-8. 2015.

Crecelius A.R., B.S. Kirby, C.M. Hearon Jr, G.J. Luckasen, D.G. Larson and F.A. Dinenno.  Contracting human skeletal muscle maintains the ability to blunt α1 -adrenergic vasoconstriction during KIR channel and Na+/K+-ATPase inhibition. J Physiol. 593(12):2735-51. 2015.

Crecelius A.R., B.S. Kirby, and F.A. Dinenno. Intravascular ATP and the regulation of blood flow and oxygen delivery in humans. Ex Sport Sci Rev. 43(1):5-13. 2015 ˄

Crecelius A.R., G.J. Luckasen, D.G. Larson and F.A. Dinenno. KIR channel activation contributes to onset and steady-state exercise hyperemia in humans.  Am J Physiol Heart Circ Physiol. 307(5):H782-91. 2014.

Crecelius, A.R. and F.A. Dinenno. Understanding ATP-mediated vasodilatation in humans: our hyper-polarizing story.  Physiology News. 94:38-44. 2014.

Crecelius A.R., J.C. Richards, G.J. Luckasen, D.G. Larson and F.A. Dinenno.  Reactive hyperemia occurs via activation of inwardly-rectifying potassium channels and Na+/K+-ATPase in humans. Circ Res. 113(8):1023-32. 2013.

Crecelius A.R., B.S. Kirby, G.J. Luckasen, D.G. Larson and F.A. Dinenno. Mechanisms of rapid vasodilatation following a brief contraction in human skeletal muscle.  Am J Physiol Heart Circ Physiol. 305(1):H29-40. 2013. ◊

Crecelius A.R., B.S. Kirby, J.C. Richards, and F.A. Dinenno.  Mechanical effects of muscle contraction increase intravascular ATP in humans.  J Appl Physiol. 114:1085-93. 2013.

Crecelius A.R., B.S. Kirby, G.J. Luckasen, D.G. Larson and F.A. Dinenno.  ATP-mediated vasodilatation occurs via activation of inwardly-rectifying potassium channels in humans. J Physiol. 590:5349-5359. 2012. **** 

Richards, J.C., A.R. Crecelius, B.S. Kirby, D.G. Larson and F.A. Dinenno.  Muscle contraction duration and fibre recruitment influence blood flow and VO2 independent of contractile work during steady-state exercise in humans.  Exp Physiol. 97:750-761. 2012.

Richards J.C., A.R. Crecelius, and B.S. Kirby.  Muscle afferent feedback during exercise: putting the pressure on flow.  J Physiol.  589:5923-5924. 2011.

Crecelius A.R., B.S. Kirby, J.C. Richards, L.J. Garcia, W.F. Voyles, D.G. Larson, G.J. Luckasen and F.A. Dinenno.  Mechanisms of ATP-mediated vasodilation in humans: modest role for nitric oxide and prostaglandins.  Am J Physiol Heart Circ Physiol. 301:H1302-H1310.  2011.

Crecelius A.R., B.S. Kirby, W.F. Voyles, and F.A. Dinenno.  Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins.  J Physiol. 589:3671-3683. 2011.

Markwald R.R., B.S. Kirby, A.R. Crecelius, R.E. Carlson, W.F. Voyles, and F.A. Dinenno.  Combined inhibition of nitric oxide and vasodilating prostaglandins abolishes forearm vasodilatation to systemic hypoxia in healthy humans.  J Physiol. 589:1979-1990. 2011. *

Crecelius A.R., B.S. Kirby, W. F. Voyles, and F.A. Dinenno.  Nitric oxide but not vasodilating prostaglandins contributes to the improvement of exercise hyperemia via ascorbic acid in healthy older adults.  Am J Physiol Heart Circ Physiol.  299:H1633-H1641.  2010.

Kirby B.S., A.R. Crecelius, W.F. Voyles, and F.A. Dinenno. Vasodilatory responsiveness to adenosine triphosphate in ageing humans.  J Physiol. 588:4017-4027. 2010.

Crecelius A.R., P.M. Vanderburgh, and L.L. Laubach.  Contributions of body fat and effort in the 5K run: age and body weight handicap.  J Strength and Cond Res.  22(5):1475-80, 2008. 

Other publications

Crecelius, A.R.. Keeping Up with the Highland Natives.  I Spy Physiology Blog. American Physiological Society. October 2016. Read more >>

Crecelius, A.R.. A 10,000-Foot View from the ALMA Observatory in Atacama.  I Spy Physiology Blog. American Physiological Society. September 2016. Read more >>

Crecelius, A.R.. In Santiago, What’s Smog Got to Do with It?  I Spy Physiology Blog. American Physiological Society. August 2016. Read more >>

Keller, J.L. and A.R. Crecelius.  Everything in moderation, including moderation (comment).  Supplementary Material to: Wisloff, U., J.S. Coombes and O. Rognmo.  CrossTalk proposal: High intensity interval training does have a role in risk reduction or treatment of disease.  J Physiol. 593(24): 5215-17. 2015. Read more >>

A.R. Crecelius. Hungry, Hungry Hormones: What Keeps You from Saying No to a Second Slice of Pie?  I Spy Physiology Blog. American Physiological Society. November 2015. Read more >>

E. A. Kelsch and A.R. Crecelius.  The impact of acute hypoxic exposure on vascular function in young, health humans: a review.  Proceedings of the Berry Summer Thesis Institute. 24-29. 2015.

A.R. Crecelius. Get a Grip: What Grip Strength Can Tell Us about the Cardiovascular System.  I Spy Physiology Blog. American Physiological Society. June 2015. Read more >>

A.R. Crecelius. Talking Physiology: Oral Exams in an Undergraduate Course.  PECOP Blog. Life Science Teaching Resource Community. April 2015. Read more >>

A.R. Crecelius. UD and DECA: Successful Stations in a Seventh-Grade Classroom for PhUn Week - PhUn Week Poster Session EB 2015. Life Science Teaching Resource Community. March 2015.  Read more >>

G.M. Kocoloski and A.R. Crecelius. Alterations and specifications of excess post-exercise oxygen consumption: a review.  Proceedings of the Berry Summer Thesis Institute.  28-32. 2014.