Angela Mammana

Assistant Professor
Full-Time Faculty
College of Arts and Sciences: Chemistry

Profile

Dr. Mammana joined the faculty in 2011.

Degrees

  • Chemistry, 2003, Ph.D., Biochemical and Biomolecular Sciences, “Università degli Studi di Catania”, Catania, Italy, 2008
  • 2009- 2010: Post-doctoral Research Assistant, University of Groningen, Groningen, The Netherlands in the lab of Prof. Ben Feringa
  • 2006- 2007: Visiting Scholar at Columbia University, New York City, NY, USA, in the lab of Prof. Koji Nakanishi

Research Interests

  • Circular Dichroism studies of biochemical (polypeptides and nucleic acids) and synthetic systems
  • Dynamic self-assembly and supramolecular chemistry
  • Chiroptical Biosensors
  • Biomacromolecule modification and conformational studies
  • Molecular switches and motors: chiroptical properties and interactions with DNA and Liquid Crystals

Selected Publications

A. Mammana, G.T. Carroll and B. L. Feringa, "Circular Dichroism of Dynamic Systems: Switching Molecular and Supramolecular Chirality." Comprehensive Chiroptical Spectroscopy, John Wiley & Sons, Ed. N. Berova, P. Polavarapu, K. Nakanishi and R. Woody, New York City, NY, 2012.

A. Mammana, G. T. Carroll, J. Areephong and B. L. Feringa, "A photoswitchable chiroptical DNA complex," Journal of Physical Chemistry B., 115 (40) 11581-11587, 2011.

R. Lauceri, A. D’Urso, A. Mammana, R. Purrello, "Transfer of Chirality for Memory and Separation," Topics in Current Chemistry, Springer-Verlag, Ed. Naaman, Ron; Beratan, David N; Waldeck, David, Berlin, 298, 143-88, 2011.

A. Mammana, G. Pescitelli, T. Asakawa, S. Jockusch, A. G. Petrovic, R. R. Monaco, R. Purrello, N. J. Turro, K. Nakanishi, G. A. Ellestad, M. Balaz and N. Berova, "Role of environmental factors on the structure and spectroscopic response of 5' -DNA- porphyrin conjugates due to changes in porphyrin-porphyrin interactions," Chemistry - A European Journal, 15, 11853–11866, 2009.

A. D'Urso, A. Mammana, M. Balaz, A. E. Holmes, N. Berova, R. Lauceri and R. Purrello, "Interactions of a Tetraanionic Porphyrin with DNA: from a Z-DNA Sensor to a Versatile Supramolecular Device," Journal of the American Chemical Society, 131 (6), 2046–2047, 2009.

R. Randazzo, R. Lauceri, A. Mammana, A. D’Urso and R. Purrello, "Interactions of - and - Enantiomers of Ruthenium(II) Complexes with Achiral Anionic Porphyrins." Chirality, 21(1), 92-96, 2009.

R. Randazzo, A. Mammana, A. D’Urso, R. Lauceri and R. Purrello, "Reversible 'Chiral Memory' in Ruthenium Tris(phenanthroline)–Anionic Porphyrin Complexes." Angewandte Chemie, 47, 9879-9882, 2008.

A. Mammana, T. Asakawa, K. Bitsch-Jensen, A. Wolfe, S. Chaturantabut, Y. Otani, X. Li, Z. Li, K. Nakanishi, M. Balaz, G. A. Ellestad and N. Berova, "Synthesis and Characterization of Water-soluble Free-base, Zinc and Copper Porphyrin-oligonucleotide Conjugates." Bioorganic & Medicinal Chemistry, 16(13), 6544-6551, 2008.

R. Lauceri, A. D'Urso, A. Mammana and R. Purrello, "Chiral Memory: Induction, Amplification, and Switching in Porphyrin Assemblies." Chirality, 20(3/4), 411-419, 2008.

A. Mammana, A. D'Urso, R. Lauceri and R. Purrello, "Switching Off and On the Supramolecular Chiral Memory in Porphyrin Assemblies." Journal of the American Chemical Society, 129, 8062-8063, 2007.

M. Balaz, K. Bitsch-Jensen , A. Mammana, G. A. Ellestad, K. Nakanishi, N. Berova, "Porphyrins as Spectroscopic Sensors for Conformational Studies of DNA." Pure and Applied Chemistry, Vol. 79, No. 4, pp. 801–809, 2007.

A. Mammana, M. De Napoli, R. Lauceri, R. Purrello, "Induction and Memory of Chirality in Porphyrin Hetero-Aggregates: the Role of the Central Metal Ion." Bioorganic & Medicinal Chemistry, 13, 5159, 2005 (invited).

M. Balaz, M. De Napoli, A. E. Holmes, A. Mammana, K. Nakanishi, N. Berova, R. Purrello, "A Cationic Zinc Porphyrin as a Chiroptical Probe for Z-DNA." Angewandte Chemie, 44, 4006, 2005.

R. Lauceri, M. De Napoli, A. Mammana, S. Nardis, A. Romeo, R. Purrello, "Hierarchical Self-Assembly of Water-Soluble Porphyrins." Synthetic Metals, 1-3, 49, 2004 (invited).